Dr. Muwen LV
Associate Professor
College of Food Science, South China Agricultural University
Email: muwen90@scau.edu.cn
Biography
Dr. Muwen LV is an associate professor who graduated from Rutgers University, USA in 2017 with a major in food science. In 2018, she joined the Food College of South China Agricultural University as the first associate professor. Her primary research focuses on the regulation of glucose and lipid metabolism by functional food and its mechanism, the interaction between circadian clock gene expression and metabolic balance, the circadian oscillation mode of circadian clock genes during the regulation of metabolism by functional food factors, and the construction and activity evaluation of functional food delivery systems. In terms of teaching, she led a project for curriculum construction at South China Agricultural University, participated in writing a textbook monograph for China's 13th Five-Year Plan for light industry project, and published relevant teaching reform papers in core journals. Regarding scientific research, she has led projects such as National Natural Science Foundation project, Guangdong Provincial Natural Science Foundation project, Guangzhou Basic and Application project, South China Agricultural University high-level talent Introduction young talent project; additionally participating in Guangdong Province Pearl River Talent Plan introduction of innovation and entrepreneurship team project (10 million yuan) as a sub-project leader. She also won first prize in the New York State Food Institute Academic Reporting Competition in 2016. Over the past five years, she has published more than 30 papers including over 20 SCI papers as first or corresponding author in top journals within the field of food science while currently supervising 10 full-time master students.
Research Interests
1. Investigation of the regulatory effects of functional food on glucose and lipid metabolism;
2. Examination of the interplay between circadian clock gene rhythmic expression and metabolic homeostasis;
3. Modulation of circadian oscillation patterns of biological clock genes during metabolism by functional food components;
4. Research on the development and efficacy assessment of a delivery system for functional food.
Teaching
1. Food Additives
2. Food Additives (in English)
3. Food Chemistry
4. Food Chemistry (in English)
5. Research Methods and Paper Writing
Selected Publications
1. Deng, Y., Ho, C.-T., Lan, Y., Xiao, J.,Lu, M.*Bioavailability, Health Benefits and Delivery Systems of Allicin: A Review.Journal of Agricultural and Food Chemistry. 2023 （IF: 6.1，中科院一区）
2. 张玮芸, Chi-Tang Ho, 吕慕雯*. 基于脂质组学研究胡椒碱对肥胖大鼠脂代谢基因昼夜节律的影响. 食品科学. 2023
3. Lin, B., Ho, C.-T., Wang, Y., Xiao, J., Lu, M.* Capsaicin alleviates the hepatic clock gene disruption and gut microbiota dysbiosis in circadian rhythm disorder mouse model. Food Science and Human Wellness. 2023, (IF: 8.022)
4. Liang, W., Ho, C.-T., Lan, Y., Xiao, J., Huang, Q., Cao, Y., Lu, M.* Capsaicin ameliorates diet-induced disturbances of glucose homeostasis and gut microbiota in mice associating with the circadian clock. Food & Function, 2023, 14, 1662 – 1673 (IF: 6.317)
5. Zhang, W., Ho, C.-T., Wei, W., Xiao, J., Lu, M.* Piperine regulates the circadian rhythms of hepatic clock gene expressions and gut microbiota in high-fat diet-induced obese rats. Food Science and Human Wellness. 2022, (IF: 8.022)
6. Lu, M.*, Chen, C., Xiao, J., Lan, Y., Li, R., Cao, Y., Huang, Q., Ho, C.-T.*Health Benefits of Bioactive Components in Pungent Spices Mediated via the Involvement of TRPV1 Channel, Trends in Food Science & Technology, 2022, 129, 266-282 (IF: 16.002)
7. Zhang, W., Ho, C.-T., Lu, M.*Piperine improves lipid dysregulation by modulating circadian genes Bmal1 and Clock in HepG2 cells. International Journal of Molecular Sciences, 2022, 23, 5611 (IF: 6.208)
8. Li, R., Xiao, J., Cao, Y.,Huang, Q., Ho, C.-T., Lu, M.* Capsaicin Attenuates Oleic Acid-Induced Lipid Accumulation via the Regulation of Circadian Clock Genes in HepG2 Cells. Journal of Agricultural and Food Chemistry, 2022, 70, 3, 794-803 (IF: 5.895）
9. Liang, W., Lan, Y., Chen, C., Song, M., Xiao, J., Huang, Q., Cao, Y.,Ho, C.-T., and Lu, M.* Modulating effects of capsaicin on glucose homeostasis and the underlying mechanism, Critical Reviews in Food Science and Nutrition, 2021; 1-19.(IF: 11.208)
10. Zhang, W., Zheng, Q., Song, M., Xiao, J., Cao, Y.,Huang, Q., Ho, C.-T., Lu, M.* The review on the bioavailability, bio-efficacies and novel delivery systems for piperine, Food & Function, 2021,12, 8867-8881 (IF: 6.317)
11. Lu, M.*The study on the teaching effectiveness of Food Additives. Journal of Qufu Normal University. 2020, 46(6): 1-5.
12. Li, R., Lan, Y., Chen, C., Cao, Y., Huang, Q., Ho, C.-T.,Lu, M.* Anti-obesity effect of capsaicin and the underlying mechanisms: A review, Food & Function, 2020,11, 7356–7370. (IF: 6.317)
13. Lu, M., Chen, C., Lan, Y., Xiao, J., Li, R., Huang, J., Huang, Q., Cao, Y., Ho, C.-T.* Capsaicin-the major bioactive ingredient of chili peppers: bio-efficacy and delivery systems, Food & Function, 2020,11, 2848-2860. (IF: 6.317)
14. Lu, M., Lan, Y., Xiao, J., Song, M., Chen, C., Liang, C., Huang, Q., Cao, Y., and Ho, C.-T.* Capsaicin ameliorates the redox imbalance and glucose metabolism disorder in insulin-resistance model via circadian clock-related mechanisms, Journal of Agricultural and Food Chemistry, 2019, 67 (36), 10089-10096. (IF: 5.895）
15. Lu, M.,Cao, Y., Xiao, J., Song, M., Ho, C.-T.* Molecular mechanisms of the anti-obesity effect of bioactive ingredients in common spices: a review, Food & Function, 2018, 9, 4569 - 4581. (IF: 6.317)
16. Lu, M.,Ho, C.-T., and Huang, Q.* Improving quercetin dissolution and bioaccessibility with reduced crystallite sizes through media milling technique, Journal of Functional Foods, 2017.10, 37: 138~146. (IF: 5.223)
17. Lu, M.,Cao, Y., Ho, C.-T., and Huang, Q.* The enhanced anti-obesity effect and reduced gastric mucosa irritation of capsaicin-loaded nanoemulsions , Food & Function, 2017.5, 8(5): 1803~1809. (IF: 6.317)
18. Lu, M., Ho, C.-T., Huang, Q.* Extraction, bioavailability, and bioefficacy of capsaicinoids, Journal of Food and Drug Analysis, 2017.1, 25(1): 27~36. (IF: 6.157)
19. Lu, M.,Cao, Y., Ho, C.-T., Huang, Q.* Development of organogel-derived capsaicin nanoemulsion with improved bioaccessibility and reduced gastric mucosa irritation, Journal of Agricultural and Food Chemistry, 2016.6.15, 64(23): 4735~4741. (IF: 5.895）
20. Lu, M.,Cao, Y., Ho, C.-T., Huang, Q.* Quercetin nanoparticles produced by wet-milling technique with enhanced dissolution rate, bioaccessibility, and antiproliferative activity on colon cancer cells , 248th National Meeting of the American-Chemical-Society (ACS), San Francisco, CA, 2014.8.10-2014.8.14 (会议论文)
21. Lu, M., Jin, P.*, Sun, C., Zheng, Y. Research Development of Postharvest Preservation Technique of Loquat, Journal of Qufu Normal University. 2011, 37(2): 89-93.
22. Xiao, J., Tian,W., Abdullah, Wang,H., Chen, M., Huang,Q., Zhang,M.,Lu, M., Song, M., Cao.Y., Updated design strategies for oral delivery systems: maximized bioefficacy of dietary bioactive compounds achieved by inducing proper digestive fate and sensory attributes, Critical Reviews in Food Science and Nutrition, 2022, DOI: 10.1080/10408398.2022.2109583
23. Wang, H. A., Tian, W., Li, Y., Yuan, Y., Lu, M., Cao, Y., Xiao, J. Intervention effects of multilayer core-shell particles on colitis amelioration mechanisms of capsaicin. Journal of Controlled Release 2022, 351, 324-340. DOI: 10.1016/j.jconrel.2022.09.041.
24. Wei, F., Lu, M., Li, J., Xiao, J., Rogers, M. A., Cao, Y., Lan, Y*. Construction of foam-templated oleogels based on rice bran protein. Food Hydrocolloids, 2022,124, 107245,
25. Liao, Z., Guo, S., Lu, M., Xiao, J., Cao, Y., Lan, Y*. Tailoring Water-Induced Multi-Component (Ceramide and Lecithin) Oleogels: Influence of Solute Added in Water. Food Biophysics, 2022,17, 84–92
26. Huang, J., Lu, M., and Ho, C.-T.* Health benefits of dietary chronobiotics: beyond resynchronizing internal clocks Food & Function, 2021, 12, 6136-6156.
27. Zhao, Z., Lu, M., Mao, Z, Xiao, J.*, Qingrong Huang, Xuechun Lin, Yong Cao*, Modulation of interfacial phenolic antioxidant distribution in Pickering emulsions via interactions between zein nanoparticles and gallic acid. International Journal of Biological Macromolecules, 2020, 152(1): 223-233. (IF: 5.162)
28. Guo, S., Lu, M., Chen, Y., Hou, T., Zhang, Y, Huang, Z., Cao, Y., M.,Rogers, Lan, Y. * Engineering water-induced ceramide/lecithin oleogels: understanding the influence of water added upon pre- and post-nucleation. Food & Function, 2020, 11, 2048-2057. (IF: 4.171)
29. Duan, Z., Zhang, W., Lu, M., Shao, Z., Huang, W., Li, J., Li, Y., Mo, J., Li, Y., Chen C. * Magnetic Fe3O4/activated carbon for combined adsorption and Fenton oxidation of 4-chlorophenol. Carbon, 2020, (IF: 8.821)
30. Lan, M., Li, H., Tao, G., Lin, J., Lu, M., Yan, R., * Huang, J.*. Effects of four bamboo derived flavonoids on advanced glycation end products formation in vitro. Journal of Functional Foods. 2020, 71: 103976.
31. Cao, J., Yan, J., Wang, Z., * Lu, M., Yue, K., Modified citrus pectins by UV/H2O2 oxidation at acidic and basic conditions: Structures and in vitro anti-inflammatory, anti-proliferative activities. Carbohydrate Polymers, 2020, 247: 116742.
32. Song, Y., Wu, M., Tao, G., Lu, M., Lin, J., Huang, J.* Feruloylated oligosaccharides and ferulic acid alter gut microbiome to alleviate diabetic syndrome. Food Research International, 2020, 137: 109410.
Dong, L., Lu, M., Gao, X., Zhang, L., Rogers, M., Cao, Y., and Lan. Y. In vitro gastrointestinal digestibility of phytosterol oleogels: influence of self-assembled microstructures on emulsification efficiency and lipase activity. Food & Function 2020, 11(11): 9503-9513.
33. Lan, Y., Lu, M., Guo, S., Nasr, P., Ladizhansky, V., Maria G Corradini, Hou, T. , Ghazani, S. M., Marnangoni, A., Rogers, M. A. * Molecular motifs encoding self-assembly of peptide fibers into molecular gels. Soft Matter, 2019, 15(45):9205-9214. (IF: 3.14)
34. Feng, K., Zhu, X., Chen, T., Peng, B., Lu, M., Zheng, H., Huang, Q., Ho, C.-T., Chen, Y., Cao, Y. * Prevention of obesity and hyperlipidemia by heptamethoxyflavone in high-fat diet-induced rats. Journal of Agricultural and Food Chemistry, 2019, 67(9): 2476-2489.
35. Lin, C., Zhang, X., Su, Z., Xiao, J., Lu, M., Cao, Y, and Chen, Y* Carnosol improved lifespan and healthspan by promoting antioxidant capacity in caenorhabditis elegans. Oxidative Medicine and Cellular Longevity, 2019:5958043.
36. Jin, P., Lu, M., Sun, C., Zheng, Y.*. Effects of Combined Treatment of Low Temperature Storage and Methyl Jasmonate on Chilling Injury and Active Oxygen Metabolism in Cold-Stored Loquat Fruits, Acta Horticulturae Sinica, 2012, 39(3): 461-468.
Research Projects
1. Guangdong Natural Science Foundation - Surface Project (Project No.: 2021A1515012124), Investigating the effects and mechanisms of capsaicin, a functional factor that regulates lipid metabolism, on the Clock gene in liver cells, 2021/01-2023/12, Principal investigator t;
2. National Youth Science Foundation of China (Project No.: 31901689), Researching the role of circadian clock gene Bmal1 in regulating lipid metabolism by capsaicin, 2020/01-2022/12, Principal investigator;
3. Guangdong Province Pearl River Talent Plan introduction of innovation and entrepreneurship team, Innovation research team for improving functional food delivery efficiency (project number: 2019ZT08N291), 2020/01-2025/12, the second core participant;
4. Basic and Applied Basic Research Project of Guangzhou Basic Research Program, Investigating the molecular mechanism of piperine regulation of lipid metabolism through core clock gene Rev-erbα (Project No.: 2023A04J0760), 2023/04-2025/03, Principal investigator;
5. High-level Talent Introduction Young Talent Project, High-level Special - Talent Research Start-up Fund at South China Agricultural University, 2018-2022, Principal investigator；
6. British Curriculum Construction Project at South China Agricultural University, 2021/11 – 2023/11,
Principal investigator.
